Association between Microalbuminuria and Hypertension in Type 2 Diabetic Patients
Most. Zannatul Ferdous *
Department of Public Health, Hamdard University Bangladesh, Munshiganj, Bangladesh.
M. A. Wahed
Department of Nutrition and Biochemistry, International Centre for Diarrheal Diseases and Rehabilitation, Dhaka, Bangladesh.
Zebunnesa Zeba
Department of Public Health and Informatics, Jahangirnagar University, Savar, Bangladesh.
*Author to whom correspondence should be addressed.
Abstract
Aims: This study aimed to investigate the relationship between microalbuminuria and hypertension in type 2 diabetic patients.
Study Design: It was a descriptive type of cross-sectional study.
Place and Duration of Study: The study was conducted in collaboration at a diabetic clinic and Hypertension and Research Centre, Rangpur, Bangladesh from January to March 2018.
Methodology: A total of 180 diabetic patients were selected purposively age ranges 30-75 years. Anthropometric as well as biochemical measurement was done. Data was collected by a semi-structured questionnaire through face to face interview and analyzed by SPSS-20.
Results: Study subjects were separated into two groups. Group 1, those with normoalbuminuria (n=49) and Group 2, those having microalbuminuria (n=131). The prevalence of microalbuminuria was 72.8%. Group 2 or microalbuminuric patients showed higher blood pressure values (113.50±8.90 mm of Hg) as compared to Group 1 (101.88±9.80 mm of Hg). The results were statistically significant (P≤0.05). Further this study showed fasting blood sugar, duration of diabetes, systolic blood pressure and high level of sCreatinine were independently associated with microalbuminuria in the study subjects. The results were also statistically significant (P≤0.05).
Conclusion: Our study revealed high prevalence of microalbuminuria in diabetic patients and has an optimistic association with blood pressure. This study suggests the need to screen for microalbuminuria early and the active management of modifiable risk factors in particular fasting blood sugar, sCreatinine, hypertension for intervention and prevention of further complications like end stage renal disease and cardiovascular diseases.
Keywords: Normoalbuminuria, microalbuminuria, macroalbuminuria, hypertension, type 2 diabetes mellitus.